First Appearance: 1962
The 52 Gang was a gang with each member representing a card in a poker deck. It was led by the Ace of Spades a.k.a. Little Notting. Other identified members include Queen of Spades, King of Spades, and 10 of Spades.
The group kidnapped Dyne O'Matick and stole the newly-developed Space Coupe. Their scheme was eventually foiled by Dick Tracy. Ace of Spades was captured and all other members were reportedly killed.
- There is no as-yet established connection between the 52 Gang and some of the other playing card themed characters in the strip, such as Queen of Diamonds or Big Ace.