Homewood was the target of Pruneface's plot to induce blindness in a large portion of the population through the distribution of tainted coffee. The city was designated a disaster area by the President of the United States.
Tracy captured Pruneface and obtained a cure for the blindness virus, which was then distributed among the citizens' of Homewood
- In real life, Homewood is a suburb of Chicago, IL located within Cook County. This lends support to speculation that Tracy's city is meant to be a fictionalized version of Chicago.